I have had this too, in latest beta, testing locally, HFS just locks up and wont respond to any requests. I actually have to close HFS and restart it.
Usually happens after I try to upload something big, or download something big with multiple connections (stream a large video for example). DivX Web Player for example will use one connection, but constantly connect and disconnect. Instead of a steady file download, if I persist with that, HFS will hang.